ABSTRACT
<p><b>OBJECTIVE</b>To determine the effect of early enteral nutrition (EN) on immune function of the patients after operation for severe abdominal trauma.</p><p><b>METHODS</b>Fourty patients who underwent operation for severe abdominal trauma were randomly divided into two groups, and received an early enteral nutrition (EN group, n=20) through jejunal nutritional tube from postoperative day 1, or parental nutrition (PN group, n=20) for 7 days. C3, IgA, IgM, IgG and CD3+, CD4+, CD8+, CD4+/CD8+ of the two groups patients were detected on the day before operation and the postoperative day 1 and 8. The infection complications were compared.</p><p><b>RESULTS</b>After 7 days, the levels of C3+, IgA, IgG, CD3+, CD4+, CD8+, and CD4+/CD8+ in EN group increased significantly compared with those in PN group (P< 0.05). The incidence of infection was 10% in EN group, while 30% in PN group (P< 0.05).</p><p><b>CONCLUSION</b>Early enteral nutrition can improve immune function and decrease postoperative infection after operation for severe abdominal trauma.</p>
Subject(s)
Adolescent , Adult , Female , Humans , Male , Young Adult , Abdominal Injuries , Allergy and Immunology , General Surgery , CD3 Complex , CD4 Antigens , CD4-CD8 Ratio , CD8 Antigens , Complement C3 , Enteral Nutrition , Immunoglobulin A , Immunoglobulin G , Postoperative PeriodABSTRACT
<p><b>OBJECTIVE</b>To investigate the diagnosis and differential diagnosis of extranodal Rosai-Dorfman disease.</p><p><b>METHODS</b>Two cases of extranodal Rosai-Dorfman disease were studied using hematoxylin-eosin, and immunohistochemical staining, along with a literature review.</p><p><b>RESULTS</b>The lesions of RDD were characterized by the presence of large histiocytes with emperipolesis, accompanied by infiltration of lymphocytes, plasma cells and other inflammatory cells. The large histiocytes had an abundant cytoplasm, pale to eosinophilic in appearance, positive for S-100 protein staining, with a vesicular nucleus and a small basophilic nucleolus in each cell.</p><p><b>CONCLUSIONS</b>Extranodal Rosai-Dorfman disease is known as an idiopathic proliferative disease of histiocytes with a distinct morphologic feature and is very rare. Differential diagnosis from other types of fibrohistiocytic proliferation lesions is recommended.</p>